Klinik und Poliklinik
für Plastische Chirurgie
und Handchirurgie
Klinik und Poliklinik für Plastische Chirurgie und Handchirurgie
Direktor: Univ.-Prof. Dr. med. H.-G. Machens
Tel. (089) 414 021 71



Carolina Centeno-Cerdas M.Sc.

Ph.D. candidate



Beruflicher Werdegang und Ausbildung

Oct 2014 – To date

Dr. rer. nat. Candidate. Laboratory of Tissue Engineering and Regeneration. Department of Plastic Surgery and Hand Surgery. Klinikum rechts der Isar - Technische Universität München


Mar 2004-Jun 2009

University of Costa Rica, Biomedical Sciences Postgraduate Program

M.Sc. in Biomedical Sciences with emphasis in Cell Physiology


Feb 2000-Dec 2003

Costa Rica Institute Of Technology, Costa Rica

Degree in Biotechnology Engineering


Mar 2000-Dec 2002

University of Costa Rica, School of Medicine

Courses in Medical Sciences




Jan 2017 – To date

Guest researcher. Rinkevich lab. Institute of Lung Biology and Disease (iLBD), Comprehensive Pneumology Center (CPC).

Helmholtz Zentrum München, Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH)


Oct 2014 – To date

Guest researcher. Laboratory of Tissue Engineering and Regeneration. Department of Plastic Surgery and Hand Surgery.

Klinikum rechts der Isar - Technische Universität München


Jan 2014 – Oct 2014

BioEngineering Research Program, Costa Rica Institute of Technology.

Foundress and Former Coordinator (During 2014). Program implementation, event management, project coordination, accounting and budgeting as well as technical support


Abr 2012-May 2012

Regenerative Medicine Unit, Epithelial Biomedicine Division, Technological, Environmental and Energy Research Center (CIEMAT), Spain, and Transplant Coordination Unit, Asturias University Central Hospital (HUCA), Spain.


Fellowship. Skin bioengineering and development of preclinical animal models for the study of human skin diseases. Under supervision of Marcela delRío and Fernando Larcher (CIEMAT), and Álvaro Meana (HUCA).


Feb 2010-To date

Biology School, Costa Rica Institute of Technology

Lecturer for the career of Biotechnology Engineering. Giving lectures and laboratory sessions of Biochemistry, Genetics, and Culture of Animal Cells. Organizing workshops, seminars and other activities in themes related to health and research in medical applications.


Apr 2009-To date

Tissue Engineering Laboratory, Centre for Biotechnology Research. Costa Rica Institute of Technology

Researcher. Optimization of in vitro production of human skin and its transplant to patients with epidermal affections. Research in Tissue Engineering, as well as bioactivity assays


Feb 2006-Sept 2014

Biological Assays Laboratory (LEBi), Faculty of Medicine, University of Costa Rica

Member of the Scientific Committee. Evaluation of research proposals and reports.


Feb 2006- Sept 2014

Department of Biochemistry, Faculty of Medicine. University of Costa Rica

Lecturer of Biochemistry. Giving lectures and laboratory sessions to students. Organizing talks and seminars in themes related to health and biochemistry.


Feb 2006- Sept 2014

School of Medicine and Biological Assays Laboratory. University of Costa Rica

Researcher. Detection and characterization of mutations in coding regions of ATP7B gene in Costa Rican patients with Wilson Disease. Design of biological dressings for inducing regeneration in skin wounds


Dec 2006-Dec 2007

Medicare Medical Services. Cartago, Costa Rica

Project Advisor. Provided support for the preparation, execution and evaluation of clinical studies, especially those with an epidemiologic component.


Oct 2007-Nov 2007

Department of Medical Genetics, University of Alberta, Edmonton, Alberta, Canada.

Fellowship. Research on genetic variants implicated on Wilson Disease and molecular techniques used for their diagnostic.

Under supervision of Dr. Diane W. Cox


Feb 2003-Feb 2009

Medical Genetics and Metabolism Department, Children’s National Hospital; and Molecular Genetics Laboratory, National Newborn Screening Program. Costa Rica

Fellowship. Collaborating with research for molecular diagnosis of inborn errors of metabolism.


Feb 2004-Dec 2005

Department of Biochemistry, Faculty of Medicine. University of Costa Rica

Assistant Instructor. Giving lectures and laboratory sessions to students


Feb 2004-Jul 2004

Biological Assays Laboratory (LEBi), Plants Biotechnology Division, University of Costa Rica

Laboratory Assistant. In charge of introducing, micro-propagating and acclimating vegetal material of pharmaceutical interest.


Feb 2000-Dec 2003

Molecular Genetics Laboratory, National Newborn Screening Program, Children’s National Hospital “Dr. Carlos Sáenz H”. Costa Rica

Researcher. Congenital Adrenal Hyperplasia due to 21 hydroxylase deficiency: Analysis of 6 mutations of gene CYP21B in patients from the National Newborn Screening Program. Graduation project, ITCR.


Feb 2003-Nov 2003

School of Biology, Costa Rica Institute of Technology, Cartago, Costa Rica

Research Student. Establishment of a protocol for in vitro culture of Plantago major.


Feb 2000-Nov 2000

Centre for Biotechnological Research (CIB), ITCR, Costa Rica

Research Project Assistant Student. In vitro micro propagation of orchids and potatoes.

Preise und Auszeichnung

Dec 2013 First place, Science Category, Costa Rica’s Ministry of Health

First Health Fair on Science and Technology, (December 11-13, 2013). Poster cathegory. Ulloa-Fernández A., L.A. Calvo-Castro, M.I. Chaves Rodríguez, M. Jarquín-Cordero, C. Centeno-Cerdas, I. Moreira, E. Arnáez, M. Navarro and M. Rojas. “Jatropha curcas: a new candidate in the search for anticancer agents”


Jan 2008 “Contributions to creativity and excellence” Award

Florida Ice&Farm. Best project in Science area.


Dic 2007 Best Research Project.

Pfizer Scientific Institute, Latin America. Second place


Oct 2001 Third Place

V Fair of Ideas and Business. Costa Rica Institute of Technology, Cartago, Costa Rica


Jan 2000-2004 Scholarship in Academic Excellence

Costa Rica Institute of Technology, Cartago, Costa Rica


Dec 1999 Honors Graduate

Sagrado Corazón de Jesús High School, Cartago, Costa Rica



Chávez MN, Schenck TL, Hopfner U, Centeno-Cerdas C, Somlai-Schweiger I, Schwarz C, Machens HG, Heikenwalder M, Bono MR, Allende ML, Nickelsen J, Egaña JT. 2016. Towards autotrophic tissue engineering: Photosynthetic gene therapy for regeneration.

Biomaterials. 75: 25–36. http://dx.doi.org/10.1016/j.biomaterials.2015.10.014


Calvo-Castro L, Ulloa-Fernández A, Portuguez-Barboza R, Centeno-Cerdas C, Guerrero-Barrantes M, Rojas-Chaves M. 2015. Evaluación de técnicas de procesamiento y almacenamiento de piel cadavérica para bancos de tejidos.

Tecnología en Marcha. Edición especial Ingeniería de Tejidos. 28 (2): 69-82.


Centeno-Cerdas C, Calvo-Castro L, Guerrero M, Alvarenga S, Chaves N & Rojas M. 2012. Costa Rican experience in the establishment of Tissue Engineering: A technological university approach. Journal of Tissue Engineering and Regenerative Medicine. 6 (Suppl. 1): 410.


Fernández Montes de Oca ML, Alape-Girón A, Artolozaga Sustacha MJ, Calvo Bolaños LA, Centeno-Cerdas C, Gómez Salas G, Granados Blanco K, Madrigal Villalobos M, Murillo Solís AG, Pinto-Tomás A, Quesada Mora S, Salas Hidalgo E, Somarribas Patterson LF, Vindas Angulo LA y Campos Rodríguez D. 2012. Aprendizaje cooperativo en un curso de bioquímica: opinión de estudiantes y efecto en su rendimiento académico. Actualidades Investigativas en Educación (INIE) 12 (1): 1-26. ISSN 1409-4703.


Rojas M, Bonilla R, Campos S, Centeno C, Del Valle C, Pacheco JP, Saborío A, Vega J, Fernández H & Leal A. Frecuencia del alelo causante de la enfermedad de Charcot-Marie-Tooth tipo axonal con herencia autosómica recesiva en la población de Palmares, Alajuela. International Journal of Tropical Biology and Conservation (Rev. Biol. Trop). 57 (Suppl.1): 381-387


Sandí M, Centeno C, Jaramillo O, Rivera J & Sánchez A. 2005.

Congenital Adrenal Hyperplasia: Molecular and Epidemiology Characterization in Costa Rica. Hormone Research. 64 (1): 327-8.


More publications can be found here